In what cases of allergy manifestations are vaccines effective?

In seasonal sensitivities, such as colds, allergies, asthma, and seasonal coughs, which are caused by the pollen of plants scattered in the air, such as trees, grasses, and grasses.

Scattered allergens in the indoor environment that have permanent manifestations, such as allergy to dust and mites in house dust, allergens related to microscopic fungi and particles scattered from the skin of pets such as cats and dogs, allergy to bee sting venom and types of ants and cockroaches.

Are allergy vaccines useful in all cases of allergies and allergic people?

Allergy vaccines can be the treatment of choice in the following cases:

  • It is not possible to avoid allergens.
  • Treatment with drugs can cause unwanted side effects and intolerance to them.
  • In cases of allergy to bee venom
In what cases are allergy vaccines not used?

In cases where the patient is in the stage of severe and frequent asthma attack.

In patients who have to take high doses of beta-blocker drugs such as atenolol and propranolol (Inderal).

In people with autoimmune diseases, cancer and diseases that weaken the immune system, as well as users of drugs that suppress and weaken the immune system, including users of high-dose corticosteroids.

In people who are allergic to certain food substances, the vaccine is not useful and it is only necessary to avoid the consumption of such special substances.

In people who are allergic to a certain drug, there is no use of a vaccine and it is only necessary to stop the relevant drug and inform your doctor as soon as possible, and if you need to continue the drug treatment, and if possible, and only with the discretion and opinion of your doctor, other alternative drugs should be used.

How to use vaccines during pregnancy If the patient is pregnant, it is better not to start injecting allergy vaccines at the beginning of pregnancy. Because, on the one hand, the sensitivity will gradually decrease with the injection of the vaccine, and on the other hand, if severe allergic reactions occur, problems will arise for the fetus, but if the patient becomes pregnant during the vaccine treatment, there is no problem with continuing the injection of allergens.

Is it necessary to do a test before starting treatment with allergy vaccines?

Yes, performing allergy skin tests while knowing the type of allergen (vaccine) also determines the intensity of sensitivity, which is effective in adjusting the amount and concentration of the patient’s vaccine. During the tests, a very small amount of different allergens is placed on the patient’s skin by scratching, and after 20 minutes, the severity of the patient’s sensitivity is determined by the degree of redness and swelling of the area.

How long does it take for vaccines to start working?

By starting the injection of allergens, the symptoms of the disease do not disappear immediately, usually in the first year of treatment, a partial recovery begins, and in the second year, a significant effect is observed, and in most cases, the effect increases in the third year, but in some people, it is necessary to continue the maintenance dose with longer intervals, up to several years. Usually, if there is no change in the symptoms of the disease after one year, the patient should be re-evaluated to increase the concentration of the vaccine or to perform additional tests.

How long is the effect of allergy vaccines stable?

In different people, this effect is different, in some it has a lifelong effect, such as children or patients who have continued the treatment for a longer period of time, in some cases, some patients must continue the injection of the vaccine for a longer period of time so that the symptoms of the disease remain under control.

Chronic itching?

Chronic itching is a common clinical problem, and patients with it are usually referred to allergy/immunology clinics to diagnose allergies. Although, in fact, allergy is a rare cause of this clinical problem. There are many underlying diseases that can cause chronic and treatment-resistant itching, including:

Primary skin diseases

Nervous system disorders

_Liver disease

_kidney Diseases

Blood disorders and diseases and cancers

Glandular diseases




Mental disorders

Examination and history play an essential role in diagnosing the underlying causes, and paraclinical evaluations based on the mentioned differential diagnoses have their own formula for each patient.

Treatment measures:

First, it should be explained to the patient that allergy is not the cause of the disease and of course allergy tests are not helpful.

Treatment should be aimed at the underlying disease

Can the injection of allergy vaccines cause reactions?

Often, the injection of allergens is uncomplicated by following the instructions of a specialist doctor, but considering that allergy vaccines contain a certain amount of allergens, there is a possibility of a reaction in rare cases, which include:

Local reactions: It is associated with swelling and redness of the injection site, which is usually normal and lasts 4 to 8 hours.

General reactions: which are very rare, but should be taken into account, may include: sneezing and swelling inside the nose and general urticaria. At the same time, very rare reactions such as shortness of breath and swelling of the throat can also be seen.

Severe reactions: which cause blood pressure to drop and asthma and shortness of breath, and if it occurs, immediate treatment is necessary. Usually, severe reactions are caused by the irregularity of the injection interval of the vaccines or the mistake in choosing the glass for the higher concentration, which happens without injecting the lower concentration. In order to be cautious and for the possibility of immediate treatment of unwanted reactions, it is recommended that the injection of allergens be done in doctors’ offices or clinics, and after the injection, the patient should be present for half an hour and be monitored.

About children

In addition to treating and controlling current allergies, allergy vaccines also prevent new allergies from occurring in the future. The starting age for allergy vaccines in children is from the beginning of 5 years.

Evaluation of positive and negative points in treatment with allergy vaccines

In the following cases, injecting allergy vaccines is correct and appropriate and should be considered:

In cases where the allergy symptoms are severe and progressive and the length and severity of the current allergy symptoms are increasing.
Cases where there is not sufficient satisfaction with the effect of the prescribed drugs or the continuous use of these drugs causes side effects and the person’s allergy is progressing.
You cannot avoid contact with allergens.
You are well prepared to start and continue a long treatment.
The issue of financing this treatment is very important for you.

Note: A part of this text was prepared from

Note: Allergy vaccines are exclusively prepared from extracts of environmental allergens and do not contain any medicinal substances or compounds containing carotene.

Tehran Allergy Clinic has a history of almost 50 years of therapeutic and specialized allergy research in Iran.


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